CMV - Cytomegalovirus |
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| 2007-12-23 | No history |  | Add My version | |
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CMV
TYPE
DNA virus
Herpes family
Oropharyngeal route
Blood transfusion
Toddlers urine !!
MATERNAL ILLNESS
Asymptomatic
Diagnosed in retrospect
Maternal REACTIVATION infeuq assoc with transmission <15
SCREENING
VACCINATION
None avail
MANAGEMENT
Supportive
FETAL ILLNESS
May follow primary maternal or reactivated maternal
1-6% women infected during preg
40% affected foetus'
Time of infection irrelevant to defects
10-20% SYMPTOMATIC @BIRTH
Non immune hydrops
IUGR
Microcephaly
Chorioretinitis
Cerebral calcifications
Hepatosplenomegaly
Hydrocephalus
Pinprick purpura
osteitis
SENSORINEURAL DEAFNESS most common
80-90% ASYMPTOMATIC @ BIRTH Later present..
Mental handicap
Hearing impairment
Visual loss
Delayed psychomotor retartdation
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